Longoria shows off her funny side at the Hot Tamales Live! show. Plus: Patrick Dempsey, Christina Aguilera and more

2 of 18

ALWAYS A BRIDESMAID?

Patrick Dempsey and Amy Adams rule the red carpet at the Hollywood premiere of their film Enchanted on Saturday. While the actors were (mostly) all smiles, the two lamented Dempsey being passed up as PEOPLE's Sexiest Man Alive. Joked Dempsey: "Always a bridesmaid, never a bride."