Holmes makes a big fashion statement with an extra-large tote and denim bell bottoms in N.Y.C. Plus: Lauren Conrad, Janet Jackson, Jessica Simpson and more

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A 'STAND UP' GUY

His character is breaking all the rules on Gossip Girl, but in real life Chace Crawford plays dutiful son to mom Dana backstage at the Stand Up For a Cure charity concert Wednesday at New York's Madison Square Garden. Headlined by Dave Matthews Band, the event brought out stars including Julia Roberts and Lindsay Lohan (not pictured).