Hollywood's Biggest Comebacks

You can't keep a big star down! See the celebs – Paula, Ben, RDJ, Drew – who've resurfaced with extra shine

MAYIM BIALIK

After rising to fame as beloved Blossom on the '90s TV series of the same name, Bialik made a few cameos before shifting her focus to school, earning a PhD in neuroscience.
The comeback: After staying out of the spotlight for 15 years, Bialik decided acting would allow her more time with her children than life as a research professor did. She hit the jackpot in 2010 when she scored the role of Dr. Amy Farrah Fowler on season 3 of the The Big Bang Theory – and earned three Emmy nominations in the years following.