Where Are They Now? Catching Up With PEOPLE'S Half Their Size Stars

See how six men and women each lost more than 100 lbs. – and went on to inspire others


Then: After attending a friend's wake and suffering a panic attack fueled by a pizza/soda/cigarette binge, the former healthcare worker, who weighed 250 lbs., "looked in the mirror and said, 'You've got to change.'"