Becoming ... Jennifer Aniston

Though she bid a tearful adieu to Friends, Jennifer Aniston has plenty to smile about. The actress says she's looking forward to her next project: starting a family. See the defining moments in the life of PEOPLE's Most Beautiful cover girl. By Serena Kappes

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BEST FRIENDS

"We kind of have a pact," Friends costar Courteney Cox told PEOPLE about Aniston (at the Screen Actors Guild Awards in 2003). "If anything ever bothers us, we don't hold it in for one second. I never have to say, 'Are you mad?' and she doesn't have to say, 'Are you upset with me?' I trust her implicitly."