Becoming ... Jennifer Aniston

Though she bid a tearful adieu to Friends, Jennifer Aniston has plenty to smile about. The actress says she's looking forward to her next project: starting a family. See the defining moments in the life of PEOPLE's Most Beautiful cover girl. By Serena Kappes

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TOP OF HER GAME

A Christian Dior-clad Aniston won her first best actress Emmy for Friends in 2002. Friends has been "the greatest nine years of my entire life," the actress said of the show that earned her the honor. "I don't know of anything she's not capable of," costar Matthew Perry gushed to PEOPLE.