February 03

Lucky Break

Isla Fisher is born to Scottish parents – a banker father and novelist mother – in the Middle Eastern country of Oman. Soon after, the family settles in Perth, Australia, where Fisher lands her first job – a lottery commercial – at age 12. "When you watch it I'm so small, I'm just a blur," she tells EW. "But I was so excited."

Romantic Comedy

At 21, Fisher moves to Europe, making a stop in Paris to study at the Jacques Lecoq International School of Theatre, before crossing paths with comedic actor Sacha Baron Cohen in London. Together, the couple moves to Los Angeles in 2002. "I was auditioning and getting many less than enthusiastic responses," she tells Elle. "Then Sacha said, 'You're the funniest girl I know. You should be doing comedies.' And I thought, Wow, that's inspiring coming from the funniest man in the world."

July 15

Crash Course

Fisher lands the riotous role of sex-crazed Gloria Cleary – Vince Vaughn's slightly stalkerish love interest – in Wedding Crashers. The film makes over $200 million and earns Fisher an MTV Movie Award. "After Wedding Crashers," she tells Esquire, "I just got so many more opportunities."

February 14

Definitely Delightful

Valentine's Day moviegoers fall in love with Fisher and Ryan Reynolds in the adorable romantic comedy Definitely, Maybe. "The biggest problem shooting [the movie] was getting thru scenes with Isla and not laughing," Reynolds tells Moviefone. Later that year, Fisher voices her first animated character, Dr. Mary Lou Larue, in Horton Hears a Who.

March 15

Vow of Silence

In Paris, Fisher and Cohen marry in a super-secret ceremony – with just six guests! "They brighten everything up a bit, but you can see that they're not just there to entertain," pal Naomi Watts gushes to Harper's Bazaar. "They're really connected to each other and are taking care of each other the entire time. It's beautiful."