After appearing as a cheating wife in Mike Nichols' Closer with Jude Law, Clive Owen and Natalie Portman, Roberts takes on her first acting gig since having twins: 12 days filming the Dave Matthews Band "Dreamgirl" music video. Why her? "I just needed the work," she jokes to PEOPLE. Adds Matthews, Roberts' longtime pal: "We thought we'd politely give her a hand up."
New mom Roberts stars for three months in a Broadway revival of Richard Greenberg's Three Days of Rain, making a reported $35,000 a week. "I'm just thrilled to my bones," she tells Playbill. However, critics aren't as excited. The New York Times finds Roberts "stiff with self-consciousness" but "so deeply, disturbingly beautiful that you don't want to let her out of your sight."
Roberts makes a foray into the world of computer-animated children's films, with The Ant Bully and as the title character in Charlotte's Web. Two weeks after the film opens, her rep confirms that the actress is expecting. She gives birth to a boy named Henry Daniel Moder in June 2007.
To promote her new film Charlie Wilson's War (with Tom Hanks and Amy Adams), Roberts appears on the cover of Vanity Fair, where she tells the magazine that she's not planning on having anymore kids. "You only have so much energy and you want to put so much energy into each child," she says. "I wouldn't know how to have five kids. And they're a really good trio, these three."
Roberts fronts her first movie in years in Duplicity, an espionage thriller with Closer costar Clive Owen. "She's got a deftness and a lightness of touch and an ease," Owen says. "She was far and away the choice for us.'' While slated as her big screen comeback, the film underperforms at the box office. But a year later, Roberts returns to the top when she reunites with Pretty Woman director Garry Marshall for the star-studded hit, Valentine's Day.
Twenty years after shining in Pretty Woman, Roberts prepares to return to her box-office perch with Eat Pray Love – an adaptation of Elizabeth Gilbert's 2006 best-selling memoir about a divorcée's journey of self-discovery. "I think she has never looked more beautiful," director Ryan Murphy tells PEOPLE of the actress. "She is so happy and fulfilled in her personal life – and it shows."
For her role as the menacing Queen Gertrude, Roberts sheds her sweetheart persona for a taste of the dark side in Mirror, Mirror, a campy and comedic adaptation of the fairy tale Snow White. "I think she's a lunatic," Roberts tells Access Hollywood of her character. "She's just crazy."
Roberts returns to the award circuit for August: Osage County, a dark play about family dysfunction that sees her face off against Meryl Streep, who plays the family's matriarch. "When I first read this script my heart just swelled and I completely understood everything about the character," the actress tells Refinery29. "I was so floored [by the writing] ... This was something that comes once in a while." The role earns Roberts Golden Globe, SAG Award and Oscar nominations.
BIOGRAPHY (top to bottom): MIKE WARING; Walter McBride/Retna; Courtesy of EW; Francois Duhamel/Columbia Pictures; Jan Thijs/Relativity Media; The Weinstein Company