Cruise jumps on Oprah Winfrey's couch to express his love for Holmes and then pulls her onto the show from backstage. Cruise's behavior prompts Winfrey to exclaim repeatedly: "You're gone!" On June 17, after two months of dating, Cruise proposes to Holmes at the Eiffel Tower. That October, the couple, dubbed "TomKat" by the press, announces Holmes' pregnancy.
After receiving harsh reviews for her turn in 2005's Batman Begins, Holmes also causes a stir at the Sundance Film Festival. At the screening of Thank You for Smoking, a nude sex scene between Holmes and costar Aaron Eckhart is mysteriously cut, leaving the movie's writer-director, Jason Reitman, shocked. The scene is later reinstated in the theatrical release.
Holmes gives birth to 7 lb. 7 oz. Suri in a L.A.-area hospital. The delivery is so smooth that Holmes leaves the hospital within 24 hours. When the couple keeps their daughter under wraps for months, Suri becomes Hollywood's most mysterious baby. Wild stories circulate.
After months of speculation and reports on her whereabouts, Suri makes her debut with her parents on the cover of Vanity Fair, photographed by legendary photographer Annie Leibovitz. "This is my future," Holmes tells the magazine. "This is my family and I care so much about them."
Holmes and Cruise wed during a star-studded ceremony at Odescalchi Castle on Lake Bracciano near Rome. Guests include Will Smith and wife Jada Pinkett, Brooke Shields, Victoria and David Beckham, Jennifer Lopez and Marc Anthony. Designer Giorgio Armani outfits the bride, groom, bridal party, and the couple's families.
The low-key girl, who couldn't pronounce Badgley Mischka on the red carpet in 1998, undergoes a style transformation. Often photographed shopping and in the front row of fashion shows, Holmes poses for the cover of Harper's Bazaar. Close friend and fashion maverick Victoria "Posh" Beckham styles her for the photo shoot.
After chopping her hair and appearing more fashionable than ever, Holmes is featured in a PEOPLE cover story. It follows her transformation from all-American girl to couture-clad mommy with 1-year-old Suri. The 28-year-old star "has a serenity about her," says Callie Khouri, her director on the bank heist comedy Mad Money. "I just think she's in a really happy place. She's obviously in love – with Tom and with her child."
After rehearsing all summer, Holmes makes her Broadway debut in the revival of Arthur Miller's All My Sons, alongside theater vets John Lithgow, Dianne Wiest, and Patrick Wilson. Cruise, sans daughter Suri, attends the show's first night of previews. "I'm so proud of her," Cruise tells PEOPLE. "This means so much to her."
Holmes returns to the big screen in the film adaptation of the acclaimed novel The Romantics. The indie flick, which also stars Josh Duhamel and Anna Paquin, earns the actress (who also serves as executive producer) shining reviews, with the Hollywood Reporter praising "the film more or less belongs to Holmes."
Holmes stars opposite Greg Kinnear in The Kennedys, an eight-part miniseries in which she and Kinnear portray Jacqueline and John F. Kennedy. But shortly before its debut, the History Channel pulls it from the air (it later airs on Reelz). "It's the truth," executive producer Michael Prupas says in response to reports that the series was historically inaccurate. "[It] is a positive reflection. But we have shown the flaws."
BIOGRAPHY (top to bottom): FOX Searchlight; Annie Leibovitz/Vanity Fair/AP; Eric Ryan/Getty; Ray Tamarra/Getty Images; Splash News Online