William will join various initiatives that build on wildlife conservation, which he famously holds dear, the palace has announced.
The prince, 31, has made videos with David Beckham and basketball star Yao Ming to highlight the campaign to reduce demand for rhino horn and ivory. And he is hoping to use the Royal Foundation, which he set up with brother Harry and with which wife Kate became involved after their 2011 marriage, to foster cooperation among seven conservation organizations.
William and Kate stepped out for a gala on Thursday to celebrate the work of one of his favorite charities, Tusk Trust, when it marks its first conservation awards. William handed out two prizes at the event.
The new partnership, United for Wildlife, is making a long-term commitment to tackle the global challenges to the world's natural resources so they can be safeguarded for future generations.
William, who will be president of the collaboration, said in a statement: "The threats to our natural heritage are extensive, but I believe that this collaboration of the best minds in conservation will provide the impetus for a renewed commitment and action to protect endangered species and habitats for future generations."
He added: "At the root of the illegal wildlife trade, for example, is the demand for products that require the deaths of tens of thousands of these animals every year, pushing them further towards extinction. We must work together to prevent this catastrophe and allow our children the opportunity to experience wildlife in its many beautiful and varied forms."