The actress, who will mark her 50th birthday on Nov. 11, is wrapping a challenging year: Her 6-year marriage to Ashton Kutcher, 34, ended last November in the wake of the actor's public cheating scandal; she was hospitalized last January; and since then she has endured intense scrutiny of her well-being.
Multiple sources close to her circle say some friends are worried Moore hasn't fully recovered. Her thinness is still raising concerns, a source tells PEOPLE in this week's cover story: "Her friends aren't convinced she's all better."
Now, with her milestone birthday fast approaching, she must cope with her ex's very public new romance with actress Mila Kunis, 29.
One source close to her says she is "jealous and frustrated" by the romance.
Another insider says the actress is taking Kutcher's cheating the hardest.
"What was humiliating was having her husband cheat on her in such a public way," the insider says. "But once that happened, she has not looked back."
But another source maintains she's doing well: "As hard as it has been, despite the depression of going through a divorce, she came through it."
For much more on how Demi is coping, her relationship with her three daughters and why Demi and Ashton have yet to finalize their divorce, pick up this week's issue of PEOPLE