The Secretary of State, who was admitted to New York Presbyterian Hospital on Sunday, did not suffer a stroke or neurological damage, her doctors say.
She is being treated with blood thinners and is "making excellent progress," says a statement from Dr. Lisa Bardack of Mt. Kisco Medical Group and Dr. Gigi El-Bayoumi of George Washington University.
"We are confident she will make a full recovery," says the statement. "She is in good spirits, engaging with her doctors, her family, and her staff."
She was discharged from the hospital on Wednesday.
The blood clot was found in the space between her brain and skull behind the right ear during an exam related to the concussion Clinton suffered during a fall earlier this month.
Clinton, 65, suffered a concussion when she passed out and fell in her Washington, D.C., home. Reports at the time said dehydration suffered after a trip the former first lady took to Europe was the cause of her fall.
Clinton, who was recently named one of Barbara Walters's 10 most-fascinating people of 2012, plans to step down from her secretary post early next year.