Moore, 59, filed a divorce petition against wife Kathleen Glynn, 55, in an Antrim County, Mich., court on June 21, noting that there was "no reasonable likelihood that the marriage can be preserved," Michigan's Mlive.com reported Friday.
Glynn worked with her husband as producer on several of his films, including Bowling for Columbine, Sicko and Fahrenheit 9/11.
The couple owned a home, valued at $1.2 million, on the state's scenic Torch Lake. They married in 1991 in Flint, Moore's hometown. He chronicled the automotive city's woes in his 1989 documentary Roger & Me, the first of of nine films. He is also the author of eight books.
Glynn, who is also from Flint, studied at Mott Community College and was a one-time contributing writer to Moore's publication, The Flint Voice.
According to reports, the divorce papers say the couple have no children and no longer live together. Moore is seeking a restraining order barring sales of joint assets.