03:23 AM EDT 12/22/2014
Originally posted 05/15/2014 02:00PM
[YOUTUBE "Z0hQ_C59cyI"] As LFO was fond of reminding us, "Michael J. Fox was Alex P. Keaton" on the hit 1980s sitcom Family Ties, a crucial part of NBC's long-running Thursday night comedy block, which ends with the network's fall 2014 schedule.
But beyond its young star, a number of famous actors also started their journey to fame and fortune with bit parts on the series. To celebrate this week's 25th anniversary of the Family Ties finale (the curtain call of which you can watch above), let's revisit some of the series' most significant cameos.
Top 5 Most Voted Stories
California High School Teacher Found Hanging in Classroom by Her Students
Tyson and Ashley Gardner Take Home Two Sets of Identical Twin Girls
Khloé Kardashian Wants to Replace Kelly Osbourne on Fashion Police
Curt Schilling Takes Down His Daughter's Cyber Bullies
Mother of 2-Year-Old with Rare Disorder Speaks Out After Internet Memes Make Fun of Her Daughter
Top 10 News Categories
The most buzzed about stars this minute!
Treat Yourself! 4 Preview Issues
More On PEOPLE.com
Got a News Tip?
Send it to our People.com editors!