01:04 PM EDT 05/24/2015

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Patrick Dempsey

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Patrick Dempsey's 10 McDreamiest Moments on Grey's Anatomy | Patrick Dempsey

Grey's Anatomy

Patrick Dempsey's 10 McDreamiest Moments on Grey's Anatomy

Originally posted 04/24/2015 12:05PM

As we say goodbye to Patrick Dempsey's dreamy doctor alter ego, Derek Shepherd, we're looking back on the 10 best moments that earned him his famous moniker.

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What's Next for Grey's Anatomy's Patrick Dempsey? | Patrick Dempsey

Grey's Anatomy

What's Next for Grey's Anatomy's Patrick Dempsey?

Originally posted 04/24/2015 10:00AM

Just because he's no longer McDreamy doesn't mean we've seen the last of Patrick Dempsey.

After 11 seasons on Grey's Anatomy, the man known to millions as Dr. Derek Shepherd has hung up his scrubs and moved on to new projects.

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FROM EW: Shonda Rhimes Gives Statement on Killing Off Grey's Anatomy Star

FROM EW: Shonda Rhimes Gives Statement on Killing Off Grey's Anatomy Star

Originally posted 04/23/2015 10:15PM

"I never imagined saying goodbye," Rhimes said in a statement to EW

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Dr. Derek Shepherd Has Died | Patrick Dempsey

Dr. Derek Shepherd Has Died

Originally posted 04/23/2015 09:45PM

World-renowned brain surgeon Derek Shepherd has died.

The talented doctor, whose car was broadsided after he helped to rescue victims of another accident, died Thursday shortly after doctors failed to properly diagnose the extent of his injuries.

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FROM EW: Grey's Anatomy Star Patrick Dempsey on Tonight's Shocking Twist | Patrick Dempsey

FROM EW: Grey's Anatomy Star Patrick Dempsey on Tonight's Shocking Twist

Originally posted 04/23/2015 09:35PM

The actor talks to EW about Thursday night's episode

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McDreamy Is Dead! Patrick Dempsey Killed off Grey's Anatomy | Patrick Dempsey

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McDreamy Is Dead! Patrick Dempsey Killed off Grey's Anatomy

Originally posted 04/23/2015 09:00PM

Did that really just happen on Grey's Anatomy?

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UpdatePosted 04/23/2015 05:00PM

Grey's Anatomy Sneak Peek: Does Derek Survive a Fiery Car Crash? (VIDEO)

Originally posted 04/21/2015 08:00PM

Meredith was left reeling in last week's episode of Grey's Anatomy when plane crash victims were rushed into Grey Sloan Memorial, reminding her of the loss of Mark and Lexie. Further heightening her anxiety was the fact that Derek was a no-show to his meeting in D.C., causing her to worry about his safety.

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The Best Scenes From Grey's Anatomy's First Episode

#TBT: The Top Grey's Anatomy Pilot Moments

Originally posted 04/09/2015 09:20PM

Oftentimes, it takes a few episodes to get really invested in a show. But from its 2005 premiere date, Grey's Anatomy sucked us in. In honor of the show's 10-year anniversary (and Thursday's new episode!), let's look back at the best moments from the show's pilot for an epic game of remember when ...

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Grey's Anatomy Turns 10: See the Cast When They First Started at Seattle Grace

Grey's Anatomy

Grey's Anatomy Turns 10: See the Cast When They First Started at Seattle Grace

Originally posted 03/27/2015 02:10PM

Ten years ago Americans got their first taste of McDreamy when Grey's Anatomy premiered on March 27, 2005.

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Grey's Anatomy

Grey's Anatomy Sneak Peek: Amelia Begs for Derek to Return to Seattle

Originally posted 03/04/2015 12:00PM

[BRIGHTCOVE "4093188664001" "" "" "auto"] Could Derek (Patrick Dempsey) be heading back to Grey Sloan Memorial?

In an exclusive sneak peek at Thursday's Grey's Anatomy, Amelia (Caterina Scorsone) freaks out over the daunting task of operating on Dr. Herman's (Geena Davis) ticking time bomb of a brain tumor.

Amelia's freakout, however, occurs at the most inopportune of times – in the operating room with a packed theater of doctors above her and with Dr. Herman anesthetized on the table.

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