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BARRY WATSON
Samantha Who? (ABC, 9:30 p.m.)
Premieres: Oct. 15
After a stint on the short-lived series What About Brian, Watson, 33, returns to ABC this season – as Christina Applegate's boyfriend. And the former 7th Heaven star knows something about bouncing back: October will mark five years since he's been in remission with Hodgkin's disease. He told Good Morning America, "I feel better than I've ever felt in my whole life."

