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MIRA SORVINO
Turned 40: Sept. 28
The Reservation Road actress has an Oscar, two babies and a husband nearly 15 years her junior, actor Christopher Backus. So what more could she want? "I'd love it," she joked to PEOPLE, "if I was independently wealthy and could stop acting and just focus on being a mom and activism." Already she's been working with the Global Fund for Children and has been vocal about human trafficking. "Help is not always reaching our most precious, vulnerable human beings," Sorvino told CNN. "You just want to scream and cry and do everything that you can."

