Most Beautiful 2008

PEOPLE's Most Beautiful in '07

Some are familiar faces, others fresh and new. Find out who made PEOPLE's Most Beautiful list last year

Patrick Dempsey

"The gray hairs certainly have come in the last few months," says the 42-year-old of the grey in his anatomy. "The last year has been difficult on many levels, with the show moving to Thursday night, and everything that happened this year, and worrying that everything was going to go all right with the boys [newborns Darby and Sullivan] and my wife [Jill, age 41]. But they've ceased to come in as quickly."

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