Sexiest Man Alive 2011
Sexiest Man Alive: Who Could Be Next?
Tom Cruise, Johnny Depp, Brad Pitt – who could inherit the crown from these past PEOPLE cover stars?
Credit: Anne Knudsen/Sygma/Corbis; Jason LaVeris/FilmMagic
Updated: Friday Nov 12, 2010 | 05:00 PM EST By: Kiran Hefa & Kate Hogan
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Nicknamed "Charmin' Harmon," St. Elsewhere star Mark Harmon joked to PEOPLE that one of the perks of his job was, "Women would come up to me and show me their breasts and ask for my opinion." Today's Dr. McDreamy Patrick Dempsey has an equally enthusiastic but tamer fan base, among them daughter Talula. "One day [she] said, 'You're very handsome, Poppy,'" Dempsey told PEOPLE.
